Evidence supporting the use of: Procyanidol
For the health condition: Skin Care (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Procyanidol, more commonly known as procyanidins or oligomeric proanthocyanidins (OPCs), are a class of polyphenolic compounds found in a variety of plants, including grape seeds, pine bark, and cocoa. Scientific studies have explored their antioxidant properties and their potential applications in skin care. Research indicates that procyanidins can neutralize free radicals, thereby protecting skin cells from oxidative stress, a key factor in skin aging and damage. Several in vitro and animal studies have demonstrated that procyanidins can help protect collagen and elastin fibers in the skin, reduce inflammation, and improve microcirculation, which can potentially support healthier skin appearance and function.
Some small clinical trials and observational studies suggest that oral supplementation with procyanidins (often from grape seed extract) may improve skin elasticity, hydration, and reduce the appearance of wrinkles, though results are variable and more robust clinical evidence is needed. Topical formulations have also shown promise in protecting against UV-induced skin damage. However, while the antioxidant and anti-inflammatory effects are well documented, large-scale, long-term human trials directly linking procyanidins to significant improvements in skin health are limited.
In summary, the use of procyanidol/procyanidins in skin care is primarily supported by scientific evidence, particularly regarding their antioxidant and protective effects. Nevertheless, while promising, the level of direct clinical evidence specifically for general skin care benefits is moderate, warranting a rating of 3 out of 5.
Other ingredients used for Skin Care (general)
aloe veraanthocyanins
apple
apricot
astaxanthin
beeswax
beet
beta-carotene
black currant
radish
sesame
bovine gelatin
catalase
colostrum
cryptoxanthin
cucumber
d-alpha tocopherol
dog rose
heartwood
hyaluronic acid
l-cysteine
l-glutathione
l-histidine
linoleic acid (LA)
lovage
lychee
magnesium
mango
mixed carotenoids
oat
omega-3 fatty acids
pumpkin
redcurrant
silicon
keratin
spinach
starch
tomato
almond fruit
Urolithin A
vitamin A
vitamin C
vitamin E
watercress
watermelon
zinc
sarsaparilla
red clover
chickweed
oryza
root tuber
birch
dulse leaf
camphor oil
goji berry
amaranth
sea salt
3,3'-dihydroxy-B-carotene-4,4'-dione
Alpha-terpineol
Azelaic acid
Arbutin
Avocado
Anserina
Ascophyllum nodosum
Alpha Hydroxy Acids
Asam gelugor
Allantoin
anthocyanidins
Algal protein
Argan nut oil
Abalone
Behenic Acid
Biopeptide
Black spruce
beta-zeacarotene
Brassica
Bisabolene
Butternut
Borage
Bottle gourd
Bird's nest
California chia
Chervil
Carnosine
Candelilla wax
Cocoa Butter
Cereal grass
Citral
Castile Soap
Copaiba Oil
Currant
Dunaliella salina
David's Milkberry
Dulse
Egg
Emu Oil
Himalayan Salt
Oak
Orchid
Rose
Snakeroot (unspecified)
Silk protein
Other health conditions supported by Procyanidol
Cardiovascular DiseaseCirculation (poor)
Diabetic Retinopathy
Edema
Free Radical Damage
Gingivitis
Inflammation
Skin Care (general)
Varicose Veins
Wrinkles