Evidence supporting the use of: Vitamin A (retinyl palmitate)
For the health condition: Skin Care (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin A (retinyl palmitate) is widely used in skin care due to its well-documented role in maintaining skin health. Retinyl palmitate is an ester form of vitamin A that is converted in the skin to retinol and subsequently to retinoic acid, the active form. Scientific evidence supports its use in promoting skin cell turnover, enhancing collagen production, and reducing signs of aging such as fine lines and wrinkles. Several clinical studies have shown that topical application of vitamin A derivatives can improve skin texture and reduce hyperpigmentation. While retinoic acid (tretinoin) is more potent and has stronger clinical backing, retinyl palmitate is valued for its lower irritation potential, making it suitable for sensitive skin or as an introductory retinoid. It is also used to support overall skin barrier function and repair. However, it is less effective than prescription-strength retinoids due to the multi-step conversion required in the skin. Overall, its inclusion in skin care products is justified by substantial scientific research, though the strength of effect is moderate compared to other vitamin A derivatives. Safety data indicate it is generally well-tolerated when used as directed, though photosensitivity and irritation can occur in some individuals.

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