Vitamin E (mixed tocopherols) is widely used in skin care, both in traditional remedies and in modern dermatology. Scientifically, Vitamin E is recognized as a potent lipid-soluble antioxidant that helps protect skin cells from oxidative damage caused by free radicals, which are generated by UV radiation and environmental pollutants. Several in vitro and animal studies demonstrate that Vitamin E can reduce UV-induced skin damage, decrease inflammation, and support wound healing. Some small human studies suggest topical Vitamin E may reduce erythema (redness) and improve skin moisture; it is often found in formulations aimed at improving skin texture and reducing signs of aging. However, clinical evidence in large, well-controlled human trials remains limited and results are mixed, especially regarding its effectiveness in reducing scars or treating chronic skin conditions beyond hydration and mild protection. Oral supplementation shows less consistent benefits for skin health compared to topical application. Overall, the use of Vitamin E in skin care is justified by its antioxidant properties and modest clinical findings, but the strength of direct clinical evidence for specific conditions (beyond general protection and hydration) is moderate.

References:

• Thiele JJ, Ekanayake-Mudiyanselage S. Vitamin E in human skin: Organ-specific physiology and considerations for its use in dermatology. Molecular Aspects of Medicine. 2007;28(5-6):646-667.
• Al-Niaimi F, Chiang NYZ. Topical Vitamin E in Dermatology: A Review. J Clin Aesthet Dermatol. 2017;10(7):49-54.
• Bouilly-Gauthier D, Jeannes C, Maubert Y, et al. Factors to consider when assessing the efficacy of antioxidants in skin care products. Antioxidants. 2021;10(2):200.