Evidence supporting the use of: Glycolic acid
For the health condition: Skin (dry and/or flaky)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Glycolic acid, an alpha-hydroxy acid (AHA) derived from sugar cane, is widely used in dermatology and skincare for its exfoliating properties. Scientific studies support its use for treating dry and flaky skin primarily due to its keratolytic effect, which helps to remove the outermost layer of dead skin cells (stratum corneum). By promoting exfoliation, glycolic acid enhances skin cell turnover and allows healthier, more hydrated skin cells to surface. This process can result in smoother, softer skin and improved moisture retention.

Clinical research demonstrates that topical application of glycolic acid (in concentrations ranging from 5% to 20%) can significantly improve skin texture, hydration, and the appearance of xerosis (dry, rough skin). For example, a randomized controlled trial published in Dermatologic Surgery (2002) found that glycolic acid-containing creams improved dry and rough skin over several weeks of use. Additionally, glycolic acid facilitates penetration of moisturizers and other active ingredients, further supporting its use in managing dry or flaky skin.

While glycolic acid is generally effective, it can cause irritation or increased sensitivity, especially in those with very sensitive or compromised skin barriers. Thus, its use should be tailored to individual tolerance levels. In summary, the scientific literature provides a solid basis for the use of glycolic acid in addressing dry and flaky skin, with moderate to strong evidence supporting its efficacy.

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Products containing Glycolic acid

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