Synopsis

Source of validity: Scientific
Rating (out of 5): 2

10-Undecenoic acid, also known as undecylenic acid, is a fatty acid derived from castor oil. Its use in the treatment and support of skin infections, particularly fungal infections such as tinea pedis (athlete’s foot), is supported by scientific evidence, though the quality and extent of this evidence are moderate. Undecylenic acid has demonstrated antifungal activity in vitro, primarily against dermatophytes, the fungi responsible for common superficial skin infections. It works by disrupting fungal cell membranes, thereby inhibiting fungal growth and proliferation.

Undecylenic acid is an FDA-approved active ingredient in over-the-counter topical antifungal products. Clinical studies are limited but generally show that it can be effective in reducing symptoms and clinical manifestations of fungal skin infections, especially when used as a component of combination therapies. Its efficacy is generally considered lower than imidazole or allylamine-based antifungals, but it remains a viable option, particularly for mild infections or in those seeking alternative treatments.

Evidence for its antibacterial activity or effectiveness for non-fungal skin infections is lacking. Overall, the scientific support for undecylenic acid in the management of fungal skin infections is real but not robust, with a rating of 2 out of 5 for evidence strength, based on the predominance of in vitro studies, historical use, and a limited number of clinical trials.

More about 10-Undecenoic Acid
More about Skin (infections)

Other ingredients used for Skin (infections)

Ajoene
Aloe vera
alpha-pinene
barberry
beeswax
bisabolol
black walnut
chlorophyll
copper
turmeric
echinacea purpurea
goldenseal
heartwood
knotweed
Japanese sophora
lactiplantibacillus plantarum
lactoperoxidase
monolaurin
quercetin
trypsin
vitamin C
zinc
bentonite
sarsaparilla
yellow root
mullein
chickweed
typhonium
paederia foetida
smilax
rubia cordifolia
privet
goldenrod
yarrow
juniper berries
sweetgums
oriental arborvitae
sheep's sorrel
queen of the meadow
wintergreen
camphor oil
stillingia
white oak
melaleuca alternifolia
10-Undecenoic Acid
15,16-Dihydrotanshinone I
3-Phenyllactic Acid
Akebia
Aquilegia viridiflora
Alpha-terpineol
Azelaic acid
Ardisia
Agave
Antirrhinum majus
Achyranthes
Alchornea
American Pawpaw
Albizia
Asafoetida
Ajuga
Aucubin
Aerva lanata
American Liverleaf
Asam gelugor
Allantoin
Aureobasidium pullulans
Alkanet
Alsonia scholaris
Ampelopsis
Acemannan
Allyl isothiocyanate
Abuta
Alkanna
Arisaema
Alantolactone
Artepillin C
Babchi
Baliospermum
Baphicacanthus cusia
Black spruce
Blepharis
Boswellic Acid
Bougainvillea
Brazilian peppertree
Bisabolene
Bael
Benzoin
Borate
Backhousia citriodora
Banyan
Bacillus
Burning Bush
Bergenia
Casearia esculenta
Croton seeds
Clerodendrum phlomidis
Citral
California Pitcher Plant
Cistus
cypress
Chaparral
Chondracanthus chamissoi
Cedrus libani
Castile Soap
Cynodon dactylon
Chiococca alba
Cocklebur
Chekiang Fritillary
Copaiba Oil
Citronella
Didymocarpus
Daphne
Emu Oil
Echinodorus
Ficus religiosa
Farnesol
Fleabane
Frankincense
Fir
Gallic Acid
Geraniol
Genipap
Glyceryl caprylate caprate
Galium
Geranial
Glycolipids
Glycyrrhetinic Acid
Gigartina
Galbanum
Golden Shower Tree
Guazuma ulmifolia
Hypericin
Hemidesmus
Homalomena
Houttuynia
Hydroxyquinoline
Hyaluronidase
Immunoglobulin G
Indian Nightshade
Indian Sarsparilla
Immortelle
Ivy
Jatoba
Kigelia africana
Kachnar
Knotgrass
Loquat
Lactobacillus plantarum
Ledebouriella
Lilium polyphyllum
Lactococcus rhamnosus
Lophira lanceolata
Lupulone
Lactic Acid
Leptadenia
Lantana camara
Leptospermum scoparium
Liverwort
Loranthus
Laminaria
Lysimachia
Labdanum
Mesua
Mountain horopito
Marjoram
Mucilage
Mountain mahogany
Matapalo Tree
Mahonia
Milkweed
Marking Nut Tree
Manzanita
Nasturtium
Night jessamine
Oak
Oldenlandia diffusa
Purple Tephrosia
Premna
Pepper Bark Tree
Polypodium
Pentatropis capensis
Plumbago zeylanica
Queen's Delight
Rosmanol
Rosa laevigata
Rhododendron
Spilanthes
Silkmoth
Streptomyces
Scoparia dulcis
Shikonin
Spikenard
Snakeroot
Silk protein
Sesquiterpenic Acid
Solanum anguivi
Sarcandra glabra
Semiaquilegia
Soapberry
Sapindus mukorossi
Semecarpus anacardium
Simaruba
Skunkvine
Sulfur
Storax
Stone Root
Smoketree
Terpinen-4-ol
Thymol
Takuna
Veronica
Verbascoside
Wrightia tinctoria
Witch Hazel
Waltheria ovata
Xanthorrhizol
Xanthoparmelia
Yellow-Fruit Nightshade
Yellow Dock

Other health conditions supported by 10-Undecenoic Acid

Athlete's Foot
Fungal Infections
Jock Itch
Skin (infections)
Thrush

Products containing 10-Undecenoic Acid

We currently have no products on Vitabase that contain this ingredient.