Evidence supporting the use of: Benzoic acid
For the health condition: Skin (infections)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Benzoic acid has a long history of use in dermatology, particularly as an antimicrobial and antifungal agent. It is most commonly found in combination with salicylic acid in topical preparations such as Whitfield's ointment, which has been used for decades to treat superficial fungal skin infections like tinea pedis (athlete’s foot) and tinea corporis (ringworm). The scientific rationale for its use lies in its ability to inhibit the growth of fungi and some bacteria by acidifying the environment, thereby disrupting microbial cell processes. Several clinical studies and dermatological texts support the efficacy of benzoic acid, especially in combination therapies, for mild to moderate superficial skin infections. However, compared to modern antifungal agents, benzoic acid is considered less potent and is now less commonly recommended as a first-line therapy. Its use is generally supported by both pharmacological studies demonstrating antimicrobial activity and by clinical experience, though the level of rigorous, high-quality randomized controlled trials is limited. Overall, benzoic acid’s use for skin infections is scientifically validated, but the strength of the evidence is moderate rather than robust, warranting a rating of 3 out of 5.

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Products containing Benzoic acid

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