Evidence supporting the use of: Black walnut
For the health condition: Skin (infections)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Black walnut (Juglans nigra) has a long-standing history in traditional herbal medicine, especially in North America and Europe, for treating various skin infections and conditions. Traditionally, the hulls of black walnut were applied topically or made into tinctures and salves to address fungal infections (such as ringworm), eczema, warts, and other skin complaints. This traditional use is largely attributed to the presence of juglone, a natural compound found in black walnut hulls, which has demonstrated antimicrobial and antifungal activity in laboratory studies. However, while in vitro studies show that juglone and black walnut extracts can inhibit the growth of some fungi and bacteria, direct clinical trials in humans for the treatment of skin infections are lacking.

Most of the evidence supporting black walnut’s use for skin infections is anecdotal or derived from folk medicine practices, rather than robust scientific studies. The evidence rating is therefore relatively low (2 out of 5), as there is a plausible biological mechanism and some laboratory data, but a lack of controlled human studies. Additionally, topical use can sometimes cause irritation or allergic reactions, so caution is advised. In summary, black walnut’s use for skin infections is primarily supported by traditional use and limited preliminary scientific evidence, but not by rigorous clinical research.

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