Evidence supporting the use of: Farnesol
For the health condition: Skin (infections)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Farnesol is a naturally occurring sesquiterpene alcohol found in the essential oils of several plants, including citronella, neroli, and lemongrass. It has garnered attention for its antimicrobial properties, particularly against bacteria and fungi that commonly cause skin infections. Several in vitro studies have demonstrated that farnesol can disrupt the growth and biofilm formation of pathogens such as Staphylococcus aureus (including MRSA) and Candida albicans. Farnesol appears to act by interfering with microbial cell membranes and quorum sensing, making it a candidate for inclusion in topical formulations targeting skin infections.

Despite these promising laboratory findings, there is limited clinical evidence supporting the efficacy of farnesol for treating skin infections in humans. Farnesol is sometimes included in cosmetic and dermatological products for its purported antimicrobial and deodorant effects, but robust clinical trials are lacking. Its use is thus primarily justified by preclinical scientific data rather than long-standing traditional use or extensive human research. The current evidence base warrants further investigation before farnesol can be considered a validated treatment for skin infections, placing the strength of scientific support at a modest level.

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Products containing Farnesol

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