Evidence supporting the use of: Hypericin
For the health condition: Skin (infections)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Hypericin is a naturally occurring compound found in the plant Hypericum perforatum (St. John’s Wort). Its use for supporting or treating skin infections is primarily rooted in traditional medicine rather than robust scientific validation. Historically, St. John’s Wort preparations, including hypericin-containing extracts or oils, have been used for centuries in European folk medicine to manage wounds, burns, and various skin ailments. The traditional application involves topical use of infused oils or extracts, believed to promote skin healing and reduce infection due to purported antimicrobial and anti-inflammatory properties.
Modern scientific investigation has identified that hypericin and related compounds possess some in vitro antimicrobial activity, particularly against certain Gram-positive bacteria, and demonstrate antiviral effects when activated by light (photodynamic action). However, clinical studies substantiating effective use of hypericin or St. John’s Wort preparations in treating skin infections in humans are limited and often methodologically weak. Therefore, while there is a basis in tradition and some preclinical evidence, high-quality clinical trials are lacking, and the use of hypericin for skin infections is not considered evidence-based by current medical standards.
Other ingredients used for Skin (infections)
ajoenealoe vera
alpha-pinene
barberry
beeswax
bisabolol
black walnut
chlorophyll
copper
turmeric
echinacea purpurea
goldenseal
heartwood
knotweed
Japanese sophora
lactiplantibacillus plantarum
lactoperoxidase
monolaurin
quercetin
trypsin
vitamin C
zinc
bentonite
sarsaparilla
yellow root
mullein
chickweed
typhonium
paederia foetida
smilax
rubia cordifolia
privet
goldenrod
yarrow
juniper berries
sweetgums
oriental arborvitae
sheep's sorrel
queen of the meadow
wintergreen
camphor oil
stillingia
white oak
melaleuca alternifolia
10-Undecenoic Acid
15,16-Dihydrotanshinone I
3-Phenyllactic Acid
akebia
Aquilegia viridiflora
Alpha-terpineol
Azelaic acid
Ardisia
Agave
Antirrhinum majus
Achyranthes
Alchornea
American Pawpaw
Albizia
Asafoetida
Ajuga
Aucubin
Aerva lanata
American Liverleaf
Asam gelugor
Allantoin
Aureobasidium pullulans
Alkanet
Alsonia scholaris
Ampelopsis
Acemannan
allyl isothiocyanate
Abuta
Alkanna
Arisaema
Alantolactone
Artepillin C
Babchi
Baliospermum
Baphicacanthus cusia
Black spruce
Blepharis
Boswellic Acid
Bougainvillea
Brazillian peppertree
Bisabolene
Bael
Benzoin
Borate
Backhousia citriodora
Banyan
Bacillus
Burning Bush
Bergenia
Casearia esculenta
Croton seeds
Clerodendrum phlomidis
Citral
California Pitcher Plant
Cistus
cypress
Chaparral
Chondracanthus chamissoi
Cedrus libani
Castile Soap
Cynodon dactylon
Chiococca alba
Cocklebur
Chekiang Fritillary
Copaiba Oil
Citronella
Didymocarpus
Daphne
Emu Oil
Echinodorus
Ivy
Oak
Spikenard
Snakeroot (unspecified)
Silk protein
Other health conditions supported by Hypericin
Cancer (natural therapy for)Depression
Herpes
Infection (viral)
Skin (infections)
Wounds and Sores