Evidence supporting the use of: Liverwort
For the health condition: Skin (infections)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Liverwort (Marchantia polymorpha and other species) has traditionally been used in folk medicine for various ailments, including skin infections and conditions. Historical texts, especially from European herbal traditions, mention the application of liverwort poultices or infusions to treat wounds, ulcers, and various skin problems. This use is largely rooted in the 'Doctrine of Signatures,' a pre-modern belief that plants resembling body organs or ailments could be used to treat those conditions—liverwort's leaf-like appearance was thought to signify its usefulness for both liver and skin ailments.

However, while some preliminary laboratory studies have identified antimicrobial and antifungal compounds in certain liverwort species, these findings are limited and do not provide robust clinical evidence for its effectiveness in treating skin infections in humans. There are no well-designed human studies or clinical trials supporting its efficacy or safety for this use. Therefore, while its application is well-documented in traditional medicine, scientific evidence remains minimal or inconclusive. The strength of evidence is rated as 2, reflecting reliance on traditional use with some supportive in vitro data but lacking substantial clinical validation.

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