Evidence supporting the use of: Lupulone
For the health condition: Skin (infections)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lupulone is a beta acid compound found in hops (Humulus lupulus) that has demonstrated notable antimicrobial activity in vitro, including against a variety of bacteria and fungi. Several laboratory studies have shown that lupulone can disrupt the cell membranes of Gram-positive bacteria, including Staphylococcus aureus and methicillin-resistant S. aureus (MRSA), both of which are common culprits in skin infections. The mechanism of action appears to involve the destabilization of bacterial cell walls and inhibition of certain enzymes critical for microbial survival.

Despite promising in vitro results, direct clinical evidence for the use of lupulone in treating skin infections in humans is limited. There are no well-controlled clinical trials or large-scale studies evaluating topical or systemic lupulone in patients with skin infections. Most of the current evidence is preclinical and limited to laboratory settings. However, the antimicrobial properties observed in these studies have spurred interest in developing lupulone-based topical formulations or incorporating it into wound dressings or other skin-care products intended to reduce microbial burden.

In summary, while there is some scientific (preclinical) evidence supporting the antimicrobial potential of lupulone relevant to skin infections, the lack of clinical studies means the evidence remains preliminary. The current evidence level is rated as 2 out of 5, indicating promising laboratory research but insufficient clinical validation.

More about Lupulone
More about Skin (infections)

Products containing Lupulone

We currently have no products on Vitabase that contain this ingredient.