Evidence supporting the use of: Paper mulberry
For the health condition: Skin (infections)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Paper mulberry (Broussonetia papyrifera) has a longstanding history of use in traditional medicine across Asia, including China, Korea, and Japan. Its bark, leaves, and roots have been used to address various skin ailments, such as infections, rashes, and inflammation. These uses are rooted in traditional beliefs that paper mulberry possesses anti-inflammatory, antimicrobial, and wound-healing properties. In traditional Chinese medicine, extracts from the plant are sometimes applied topically for skin problems, often as part of multi-herb formulations.

Scientific research on paper mulberry is limited but suggests the plant contains bioactive compounds such as flavonoids, prenylated flavonoids, and alkaloids, some of which exhibit antimicrobial activity in vitro. However, clinical evidence regarding its efficacy in treating skin infections in humans is lacking. The majority of supporting evidence comes from ethnobotanical reports and traditional texts rather than rigorous clinical trials. Therefore, while there is some preliminary scientific rationale for its use, the primary justification for using paper mulberry in the treatment of skin infections remains traditional rather than scientifically validated.

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