Evidence supporting the use of: Plumbago zeylanica
For the health condition: Skin (infections)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Plumbago zeylanica, commonly known as Ceylon leadwort or chitrak, has a long history of use in traditional medicine systems such as Ayurveda and Siddha, particularly for treating various skin conditions and infections. Traditional healers have utilized root paste, decoctions, and powders of Plumbago zeylanica for their purported antimicrobial, anti-inflammatory, and wound-healing properties. In Ayurvedic texts, it is described as an ingredient in formulations for treating skin diseases like leprosy, ringworm, scabies, and other dermatological disorders.

Some preliminary scientific studies provide limited evidence supporting its traditional use. In vitro studies have demonstrated that extracts of Plumbago zeylanica possess antimicrobial activity against certain bacteria and fungi that can cause skin infections. Additionally, the plant contains plumbagin, a naphthoquinone compound, which has shown antibacterial, antifungal, and anti-inflammatory effects in laboratory settings. However, these findings are mostly from cell-based or animal studies, with a paucity of robust clinical trials in humans.

Overall, while traditional use for skin infections is well documented and some laboratory studies lend partial support, there is a lack of high-quality clinical evidence. Therefore, the use of Plumbago zeylanica for skin infections is primarily justified by tradition, with a moderate level of supporting evidence.

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