Evidence supporting the use of: Silk protein
For the health condition: Skin (infections)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Silk protein, particularly its constituent fibroin, has been investigated for its potential to support skin healing and treat skin infections. Scientific studies have explored the use of silk-based biomaterials in wound dressings due to their biocompatibility, mechanical strength, and minimal immune response. Some in vitro and in vivo studies suggest that silk fibroin can promote skin regeneration, accelerate wound healing, and provide a suitable environment for cell growth. Additionally, silk proteins can be engineered to have antimicrobial properties, either inherently or through blending with antibacterial agents, which may help reduce the risk of infection.

However, while preclinical research is promising, clinical evidence in humans remains limited. Most studies involve animal models or laboratory-based investigations rather than large-scale human trials. Silk-based dressings are commercially available and are used in some clinical settings, but their specific efficacy in treating skin infections, as opposed to general wound healing, is not robustly established. Therefore, while there is a scientific rationale and some supportive evidence for using silk protein in skin-related applications, particularly as a wound dressing material, the strength of clinical evidence for treating skin infections specifically is moderate at best.

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Products containing Silk protein

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