Evidence supporting the use of: Sulfur
For the health condition: Skin (infections)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Sulfur has a long history of use in dermatology, and its efficacy for certain skin infections and conditions is supported by scientific evidence. Sulfur possesses keratolytic, antibacterial, and antifungal properties, which make it effective in treating various skin disorders such as acne, seborrheic dermatitis, and scabies. Its antimicrobial activity is primarily attributed to its ability to inhibit the growth of bacteria like Propionibacterium acnes and fungi involved in superficial skin infections.

Topical sulfur preparations are commonly included in over-the-counter acne treatments, and several clinical studies have shown that sulfur, alone or in combination with other agents (such as resorcinol), can reduce acne lesions and improve skin appearance. In the treatment of scabies, sulfur ointment (usually at a concentration of 5-10%) is considered an effective and inexpensive option, particularly for infants or individuals who cannot tolerate other medications.1,2

While sulfur is less commonly the first-line treatment for many skin infections today due to the availability of more modern agents, its use remains scientifically validated for mild acne, seborrheic dermatitis, and as an alternative for scabies. The evidence base includes randomized controlled trials and case series, and sulfur’s role is acknowledged in dermatological guidelines.3

References: 1. Del Rosso JQ. J Clin Aesthet Dermatol. 2013; 2. Strong M, Johnstone P. Cochrane Database Syst Rev. 2007; 3. James WD, Berger TG, et al. Andrews’ Diseases of the Skin, 13th Edition.

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Products containing Sulfur

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