Evidence supporting the use of: Azelaic acid
For the health condition: Skin (oily)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Azelaic acid is supported by scientific evidence for its use in managing oily skin, primarily due to its efficacy in treating conditions that often involve increased sebum production, such as acne vulgaris. Azelaic acid is a naturally occurring dicarboxylic acid that exhibits antimicrobial and anti-inflammatory properties. Several clinical studies have demonstrated that topical azelaic acid (typically in concentrations of 15-20%) can reduce lesions and inflammation in acne, which is frequently associated with oily skin. Its mechanism of action includes inhibition of the growth of Propionibacterium acnes and reduction of keratin production, which can help prevent clogged pores—a common issue in oily skin types. Moreover, some research suggests that azelaic acid can normalize the differentiation of follicular epithelial cells, further supporting its use in conditions of excess oil production. However, while there is moderate scientific support for its use in acne, which is related to oily skin, direct evidence for azelaic acid reducing sebum production or oiliness per se is limited. Most benefits for oily skin are inferred from its effects on acne and overall skin texture improvement. Therefore, while not a direct sebum-reducing agent, azelaic acid is a scientifically validated ingredient for managing some of the consequences of oily skin.

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Products containing Azelaic acid

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