Evidence supporting the use of: Albizia julibrissin
For the health condition: Sleep (restless and disturbed)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Albizia julibrissin, commonly known as the silk tree or mimosa, has a long history of traditional use in East Asian herbal medicine, particularly in Traditional Chinese Medicine (TCM). It is known as "He Huan Pi" or "He Huan Hua" in Chinese and is traditionally used for its calming, mood-supporting, and sleep-promoting effects. Historical texts and materia medica describe its use for alleviating insomnia, restlessness, anxiety, and emotional disturbances. The bark and flowers are both employed as mild sedatives and are thought to "calm the spirit" and relieve irritability.

In terms of scientific validation, there are a limited number of preclinical studies suggesting possible anxiolytic and sedative effects in animal models, with mechanisms proposed to involve modulation of neurotransmitters such as serotonin and GABA. However, rigorous human clinical trials are lacking, and there is insufficient evidence from modern pharmacology to confirm its efficacy or safety for sleep disorders in people. Thus, while there is a strong traditional basis and some preliminary pharmacological investigation, the clinical evidence is not robust. The overall evidence rating is moderate (2/5), reflecting strong traditional use but limited scientific support.

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