Evidence supporting the use of: Baikal Skullcap
For the health condition: Sleep (restless and disturbed)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Baikal Skullcap (Scutellaria baicalensis) has been used in traditional Chinese medicine (TCM) for centuries, primarily to "clear heat," calm the mind, and promote relaxation. In traditional practice, it is sometimes included in formulas aimed at addressing symptoms such as irritability, restlessness, and insomnia—especially when these are attributed to internal "heat" or agitation. The roots of the plant contain flavonoids such as baicalin, baicalein, and wogonin, which are believed to contribute to its traditional calming effects.

While there is a long history of traditional use for symptoms related to restlessness and disturbed sleep, direct scientific validation for Baikal Skullcap as a sleep aid is limited. A few preclinical (animal) studies suggest that some constituents may have anxiolytic (anxiety-reducing) or sedative effects, potentially through modulation of GABAergic activity in the brain. However, well-designed clinical trials in humans specifically evaluating its efficacy for insomnia or sleep disturbances are lacking. Most available evidence comes from animal models and in vitro studies, and the results have not been consistently replicated in humans.

In summary, Baikal Skullcap's use for sleep disturbances is primarily justified by tradition, with only modest and indirect support from early pharmacological research. Its evidence rating is low due to the absence of robust human clinical trials directly addressing sleep quality or insomnia.

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