Evidence supporting the use of: Iron
For the health condition: Sleep (restless and disturbed)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Iron is scientifically recognized as a potentially important factor in sleep health, particularly in the context of restless and disturbed sleep associated with Restless Legs Syndrome (RLS) and Periodic Limb Movement Disorder (PLMD). Several studies have demonstrated that iron deficiency—especially low brain iron—is linked to an increased risk and severity of RLS, a condition known to disrupt sleep due to uncomfortable urges to move the legs, especially at night. RLS is frequently found in individuals with iron deficiency, and supplementation with oral or intravenous iron has been shown in randomized controlled trials to improve symptoms and, by extension, sleep quality in patients with documented iron deficiency. The mechanism is thought to relate to iron's role in dopamine metabolism and neurotransmitter function in the central nervous system. However, for the broader population without RLS or clear iron deficiency, the evidence that iron supplementation improves sleep quality is limited. Routine use of iron to treat general sleep disturbances is not broadly supported and may carry risks if not medically indicated. Thus, iron should only be used to support sleep in individuals with medically diagnosed iron deficiency or related movement disorders, and under the supervision of a healthcare provider.

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Products containing iron

Vitabase Active Man's Formula
Vitabase Active Woman's Multi
Douglas Laboratories Amino-Iron ™
Metagenics Axis Endo™ Mango
Thorne Basic Prenatal Multivitamin
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Collagenics®
Designs For Health DFH Complete Multi™ with Copper & Iron
Vitabase Easy Iron
Metagenics Fem Prenatal®
Thorne Ferrasorb
Designs For Health Ferrochel® Iron Chelate
Metagenics GI Sustain™ Powder
Douglas Laboratories Hair, Skin and Nails Plus
Metagenics Hemagenics
Metagenics Hemagenics
Thorne Iron Bisglycinate NSF
Pure Encapsulations Iron-C
Integrative Therapeutics Iron Complex
Integrative Therapeutics K-PAX MitoNutrients
Metagenics Ketogenic Shake Chocolate
Metagenics Ketogenic Shake Vanilla
Klean Athlete Klean Isolate™ Natural Chocolate Flavor
Klean Athlete Klean Recovery ™
Pure Encapsulations Liquid Iron
Integrative Therapeutics Liquid Iron
Thorne MediClear Plus
Metagenics MetaKids Nutrition Powder Chocolate
Metagenics MetaKids Nutrition Powder Vanilla
Pure Encapsulations Mineral 650
Metagenics Multigenics®
Metagenics Multigenics Chewable Orange
Metagenics Multigenics Intensive Care
Pure Encapsulations Nutrient 950®
Pure Encapsulations Nutrient 950®
Pure Encapsulations Nutrient 950®
Pure Encapsulations OptiFerin-C
Designs For Health Organ Synergy™ 180 Capsules
Designs For Health Organ Synergy™ Powder
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™ Detox Program
Designs For Health PaleoCleanse Plus™Chocolate Detox Kit
Designs For Health PaleoGreens®
Designs For Health PaleoGreens®
Designs For Health PaleoMeal®
Metagenics Perfect Protein® Pea & Rice Chocolate Powder
Metagenics Perfect Protein Pea & Rice Vanilla Powder
Metagenics Perfect Protein Whey Chocolate
Integrative Therapeutics Physicians Elemental Diet Dextrose Free
Integrative Therapeutics Physician's Elemental Diet
Integrative Therapeutics Physician's Elemental Diet
Integrative Therapeutics Physicians Elemental Diet Kit
Metagenics PhytoGanix® Tropical Fruit
Metagenics PhytoMulti With Iron
Designs For Health Phytotein™
Designs For Health Plant Protein Cleanse
Designs For Health Plant Protein Cleanse Plus™ 570g
Designs For Health Plant Protein Meal
Designs For Health Plant Protein Meal Plus
Designs For Health Plant Protein Meal
Metagenics PlusOne® Daily Prenatal Packs
Douglas Laboratories Prenatal
Pure Encapsulations PreNatal Nutrients
Pure Encapsulations PreNatal Nutrients
Designs For Health Prenatal Pro™
Pure Encapsulations PureLean® Protein
Pure Encapsulations PurePals with Iron
Designs For Health PurePea™
Douglas Laboratories Timed Release Iron
Metagenics Ultra Calm® Bar Chocolate Coconut
Metagenics Ultra Energy Bar Caramel Sea Salt
Metagenics Ultra Glucose Control® Chocolate
Metagenics Ultra Glucose Control Chocolate
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Protein Bar Peanut Butter
Metagenics UltraClear Detox Powder
Metagenics UltraClear Plus® Detox Powder
Metagenics UltraClear Plus Detox Powder Berry
Metagenics UltraClear Plus Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Vanilla
Metagenics UltraClear RENEW Detox Powder Berry
Metagenics UltraClear RENEW Detox Powder Chai
Metagenics UltraClear RENEW Detox Powder Vanilla
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraMeal Advanced Protein® Dutch Chocolate
Metagenics UltraMeal Advanced Protein French Vanilla
Metagenics UltraMeal Advanced Protein Plain
Metagenics UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics UltraMeal Cardio 360° Pea/Rice Vanilla
Metagenics UltraMeal® Daily Support Dutch Chocolate
Metagenics UltraMeal Daily Support Mixed Berry
Metagenics UltraMeal Rice Vanilla
Metagenics Wellness Essentials Women's Daily Packs
Thorne Whey Protein Isolate Chocolate NSF
Designs For Health WheyCool™