Evidence supporting the use of: Lactucopicrin
For the health condition: Sleep (restless and disturbed)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Lactucopicrin is a bitter sesquiterpene lactone found in plants like Lactuca virosa (wild lettuce), which has a long history of use in traditional herbal medicine for its purported sedative and hypnotic effects. Historical records and ethnobotanical sources describe wild lettuce as "lettuce opium," referencing its milky latex, which was used as a folk remedy to promote sleep and calm restlessness. However, the scientific evidence supporting these claims is limited. The sedative effect is primarily based on anecdotal reports and old herbal texts. There are a few animal studies suggesting that lactucopicrin and related compounds may have some sedative or analgesic properties, but rigorous clinical studies in humans are lacking. As a result, the use of lactucopicrin to support sleep, especially for conditions like restless and disturbed sleep, is justified mainly by tradition rather than modern scientific validation. More research is needed to confirm any direct efficacy or safety for this indication.

More about Lactucopicrin
More about Sleep (restless and disturbed)

Other health conditions supported by Lactucopicrin

Anxiety
Pain (general remedies for)
Sleep (restless and disturbed)
Stress

Products containing Lactucopicrin

We currently have no products on Vitabase that contain this ingredient.