Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alpha-cyclodextrin is a type of soluble dietary fiber derived from starch. Its use in support of the small intestine and digestive health is primarily based on its functional properties as a fiber. Several clinical studies indicate that alpha-cyclodextrin can help modulate postprandial (after-meal) blood glucose and lipid levels by interfering with the absorption of dietary fats and carbohydrates in the small intestine. This modulation is believed to occur because alpha-cyclodextrin forms complexes with dietary fats, making them less available for absorption, and slows the digestion and absorption of carbohydrates.

While these effects can indirectly support small intestine function by reducing digestive load and promoting a healthier metabolic profile, the evidence for direct benefits to small intestine health—such as improving intestinal barrier function or preventing specific diseases—is limited. Most human studies focus on metabolic outcomes (e.g., cholesterol, triglyceride, or blood glucose levels) rather than direct measures of small intestinal health or function.

Currently, the use of alpha-cyclodextrin as a dietary supplement is supported by modest scientific validation for metabolic support, with its fiber properties providing some rationale for digestive benefits. However, robust clinical evidence specifically linking alpha-cyclodextrin to enhanced small intestine health remains limited, placing its evidence rating at 2/5 for this particular application.

More about Alpha-cyclodextrin
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Other body systems supported by Alpha-cyclodextrin

Digestive System
Gastrointestinal Tract
Intestinal System
Large Intestines (Colon)
Small Intestines

Products containing Alpha-cyclodextrin

We currently have no products on Vitabase that contain this ingredient.