Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Amino acids are the building blocks of proteins and play a key role in supporting the function and health of the small intestine. There is robust scientific evidence indicating that certain amino acids, such as glutamine, are critical for the maintenance of the intestinal mucosa and the integrity of the gut barrier. Glutamine, in particular, serves as a primary energy source for enterocytes (the absorptive cells lining the small intestine), and has been shown in both animal and human studies to promote intestinal healing, reduce intestinal permeability, and support immune function within the gut. Other amino acids, like arginine and threonine, are also important for mucin production and immune responses in the gut. Supplementation with specific amino acids has been investigated in clinical scenarios such as short bowel syndrome, inflammatory bowel disease, and after gastrointestinal surgery, with some studies demonstrating improved outcomes related to nutrient absorption and mucosal recovery. While not all amino acids are equally vital for the small intestine, and not all claims are equally well-supported, the use of certain amino acids for supporting small intestine health is based on a solid foundation of experimental and clinical research.

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Douglas Laboratories Free Form Amino