Evidence supporting the use of: Cholic acids (unspecified)
For the body system: Small Intestines
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Cholic acids, specifically the primary bile acid known as cholic acid, have a scientifically validated role in supporting the small intestine’s function. Cholic acid is synthesized in the liver and secreted into the intestine where it plays a critical role in the emulsification and absorption of dietary fats and fat-soluble vitamins. Cholic acid and other bile acids act as natural detergents, breaking down large fat globules into smaller micelles, which can then be absorbed by the intestinal mucosa.
In clinical medicine, cholic acid is used as a therapeutic agent in certain rare genetic disorders affecting bile acid synthesis, such as bile acid synthesis defects and peroxisomal disorders, where supplementation can restore normal bile acid pools and support proper digestion and absorption in the small intestine. This use is supported by regulatory agency approvals (such as the FDA approval for cholic acid in these settings) and documented literature. Furthermore, disturbances in bile acid homeostasis are known to contribute to malabsorption syndromes, highlighting the essential role of cholic acids in small intestinal health and function.
Therefore, the use of cholic acids to support the small intestines is primarily based on solid scientific understanding and clinical application, rather than historical or traditional use. However, outside of rare metabolic conditions, supplementation is not generally indicated for the healthy population.
More about Cholic acids (unspecified)
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Other body systems supported by Cholic acids (unspecified)
Digestive SystemGall Bladder
Gastrointestinal Tract
Hepatic System
Intestinal System
Liver
Small Intestines