Enzyme blends, typically containing digestive enzymes such as amylase, protease, and lipase, are used to support the small intestines by aiding in the breakdown and absorption of nutrients. The scientific rationale for their use is based on the fact that the small intestine is the primary site of nutrient digestion and absorption. Several clinical studies have shown that supplemental digestive enzymes can be beneficial, particularly in individuals with enzyme insufficiency conditions such as pancreatic insufficiency, cystic fibrosis, and certain gastrointestinal disorders (Opara, 2014).

For the general population, evidence suggests that enzyme supplements may help alleviate symptoms like bloating, gas, and indigestion after meals, especially with high-fat or high-protein foods (Zhang et al., 2017). However, most of the robust scientific evidence comes from studies involving people with existing digestive function impairments rather than healthy individuals. The use of enzyme blends is generally considered safe, and their mechanism — supplementing the body’s own enzyme production — is well understood and supported by biochemistry.

In summary, the use of enzyme blends to support the small intestines is scientifically valid, particularly in populations with known digestive enzyme deficiencies. The strength of evidence is moderate to strong (4/5) due to the specificity of benefit to those with impaired digestion rather than the general population.