Synopsis

Source of validity: Scientific
Rating (out of 5): 3

L-glutamine is an amino acid that is often used to support the health of the small intestine, particularly in the context of "leaky gut" or increased intestinal permeability. Scientific evidence supports its role in intestinal health, though most studies are preclinical or involve specific clinical scenarios, such as patients with short bowel syndrome, critical illness, or following chemotherapy. Research indicates that glutamine serves as a key fuel source for enterocytes (the cells lining the small intestine) and may help maintain the integrity of the intestinal mucosa. Some clinical trials have shown that glutamine supplementation can reduce intestinal permeability and improve gut barrier function under stress or injury. However, evidence for its use in otherwise healthy individuals, or for general gut health, is limited. A 2017 review in Nutrients concluded that glutamine can be beneficial for gut barrier function, particularly in states of stress or injury, but called for more robust human trials. Overall, while the biological rationale is strong and there is supportive evidence in specific medical contexts, the evidence for routine use in the general population is moderate, not definitive.

More about l-glutamine
More about Small Intestines

Other ingredients that support Small Intestines

Other body systems supported by l-glutamine

Products containing l-glutamine

Douglas Laboratories 5-HTP Plus Formula
Designs For Health Amino-D-Tox™
Designs For Health Amino-D-Tox™
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Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Thorne EnteroMend NSF
Pure Encapsulations EpiIntegrity
Pure Encapsulations G.I. Fortify
Pure Encapsulations G.I. Fortify
Pure Encapsulations G.I. Integrity
Pure Encapsulations G.I. Integrity
Designs For Health GI Revive®
Designs For Health GI Revive®
Metagenics GI Sustain™ Powder
Metagenics Glutagenics® powder
Integrative Therapeutics Glutamine Forte Drink Mix
Vitabase HGH Complex
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Klean Athlete Klean Essential Aminos + HMB®
Klean Athlete Klean Isolate ™
Thorne L-Glutamine
Pure Encapsulations l-Glutamine
Designs For Health L-Glutamine
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Pure Encapsulations l-Glutamine 850 mg
Pure Encapsulations l-Glutamine 850 mg
Designs For Health L-Glutamine Powder
Designs For Health L-Glutamine Powder
Douglas Laboratories L-Glutamine Powder
Thorne L-Glutamine Powder NSF
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Thorne MediClear Plus
Integrative Therapeutics Multiplex-1 No-Iron
Douglas Laboratories Muscle Protect™ with HMB®
Designs For Health Neurolink™
Integrative Therapeutics Nutrivitamin No-Iron
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Metagenics Ultra Potent-C 1000
Metagenics Ultra Potent-C Chewable
Metagenics UltraClear Plus® Detox Powder
Metagenics UltraClear Plus Detox Powder Berry
Metagenics UltraClear Plus Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Vanilla
Metagenics UltraClear RENEW Detox Powder Berry
Metagenics UltraClear RENEW Detox Powder Chai
Metagenics UltraClear RENEW Detox Powder Vanilla
Pure Encapsulations UltraDetox 10-Day Pure Pack
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana