Lactalbumin, also known as whey protein, is a major protein found in milk. Its use in supporting the small intestine is primarily based on its high nutritional value and bioactive peptide content. Scientific studies suggest that some components of lactalbumin, especially in hydrolyzed forms, may provide benefits for gut health, including the small intestine. These benefits are due to its easily digestible amino acids and bioactive peptides that can promote gut mucosal healing and support immune function.

Research indicates that whey proteins, including lactalbumin, can enhance intestinal barrier function and stimulate the production of glutathione, a key antioxidant in the gut. Some animal and in vitro studies have demonstrated protective effects against intestinal inflammation and support for recovery from intestinal injury. Additionally, certain peptides derived from lactalbumin have shown antimicrobial activity that may help modulate gut microbiota.

However, while there is a scientific basis for the general gut health benefits of lactalbumin, direct evidence for its targeted use in supporting the small intestine specifically (for example, in treating small intestinal diseases) is still emerging and not conclusive. Most human clinical trials focus on broader digestive or immune health rather than small intestine-specific outcomes. Therefore, the evidence supporting its use for the small intestine is rated moderate (2/5), reflecting some supportive data but not strong, targeted clinical validation.