Evidence supporting the use of: Peptidase
For the body system: Small Intestines
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Peptidase is an enzyme that plays a crucial role in protein digestion by breaking down peptides into amino acids, which can then be absorbed by the small intestine. The use of peptidases (also known as proteases) as dietary supplements is scientifically justified for supporting the small intestine’s function, especially in individuals with digestive enzyme insufficiency or certain gastrointestinal disorders. Scientific studies indicate that supplemental peptidases can aid in the digestion of proteins, potentially reducing symptoms such as bloating, gas, and discomfort associated with protein malabsorption. For example, research has shown that proteolytic enzyme supplements can improve protein digestion in conditions like pancreatic insufficiency and some food intolerances. Additionally, some clinical trials have demonstrated that enzyme blends containing peptidase may help alleviate symptoms in patients with irritable bowel syndrome (IBS) or lactose intolerance by supporting the breakdown of otherwise problematic dietary components. However, evidence is moderate rather than strong, and most benefits are noted in populations with specific digestive challenges rather than the general population. There is no significant historical or traditional use of isolated peptidase for gut health, as enzyme supplementation is a relatively modern intervention. In summary, scientific evidence does support the use of peptidase to aid small intestinal digestion, particularly in targeted populations, but more robust, large-scale studies are needed to confirm benefits for broader use.
Other ingredients that support Small Intestines
2'-Fucosyllactosealoe vera
alpha-galactosidase
amino acids
amylase
amylopectin
asparagus
bacillus clausii
bacillus coagulans
bacillus subtilis
bayberry
berberine
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
broccoli
rice
brussel sprouts
butyrate triglyceride
caprylic acid
carrot
chia seed
chicory
cinnamon
coating
colostrum
turmeric
endo-peptidase
exo-peptidase
fennel
fenugreek
fiber blend (proprietary)
flavonols
flaxseed
folate
fructooligosaccharides (FOS)
fungal protease
ginger
green banana
green tea
gurmar
cellulose
immunoglobin G
inulin
isomalto-oligosaccharide
kale
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-alanyl-l-glutamine
l-glutamine
lactase
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lactoferrin
lemon
lipase
magnesium
marshmallow
medium chain triglycerides (MCT)
microbial enzymes (proprietary)
n-acetyl-glucosamine
okra
ox bile
pancreatin
parsley
pear
peptidase (DPPIV)
phellodendron amurense
phenolic acids
phospholipids
phytase
potato starch
prebiotic blend (proprietary)
prolyl endopeptidase (PEP)
protease
protein
butyric acid
pumpkin
saccharomyces boulardii
sardines
slippery elm bark
soybean
spinach
starch
streptococcus thermophilus
sucrase
sulforaphane glucosinolate
tributyrin
vitamin A
vitamin B
vitamin D
vitamin D3
seaweed
water
watermelon
xylooligosaccharides
zinc
papaya
pterocarpus marsupium
lingzhi
yarrow
bile salt
sodium salt
dioscorea
electrolytes blend (proprietary)
polyphenols
trace minerals
purslane
fungal enzymes blend (proprietary)
millet seed
herbal blend (proprietary)
chickpea protein
enzymes blend (proprietary)
cayenne pepper
ashitaba
Aminopeptidase
Alchornea
Alpha-glycans
Alchemilla
Agrimonia pilosa
Asteracea
Acemannan
Algal protein
Arabinoxylan
Animal protein
Black Seed
Bifidobacterium
Bacillus indicus
Bifidobacterium adolescentis
Brassica
Bran
Bael
Butternut
Bacillus licheniformis
Bile
Bifidobacterium animalis
Bee products
Bitter principals
Bacteria
Bifidobacteria
bile acid
Bacillus
Buckwheat
Boerhavia diffusa
Bottle gourd
Centella triterpenes
Curry leaf
Cowpea
Cinnamomum
Carvacrol
Cape Aloe
Citrus
Cruciferous
Chitin-Glucan Complex
Corktree
Clostridium butyricum
Debaryomyces hansenii
Diamine Oxidase
Enterococcus
Egg
Eucheuma
Enzyme Blend
Egg protein
Fig
Fiber
Flavonoids
Goldthread
Galactosidase
glucose
Milk Protein
Mimosa
Soy Protein
Other body systems supported by Peptidase
Digestive SystemGastrointestinal Tract
Intestinal System
Small Intestines