Evidence supporting the use of: Peptidase
For the body system: Small Intestines
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Peptidase is an enzyme that plays a crucial role in protein digestion by breaking down peptides into amino acids, which can then be absorbed by the small intestine. The use of peptidases (also known as proteases) as dietary supplements is scientifically justified for supporting the small intestine’s function, especially in individuals with digestive enzyme insufficiency or certain gastrointestinal disorders. Scientific studies indicate that supplemental peptidases can aid in the digestion of proteins, potentially reducing symptoms such as bloating, gas, and discomfort associated with protein malabsorption. For example, research has shown that proteolytic enzyme supplements can improve protein digestion in conditions like pancreatic insufficiency and some food intolerances. Additionally, some clinical trials have demonstrated that enzyme blends containing peptidase may help alleviate symptoms in patients with irritable bowel syndrome (IBS) or lactose intolerance by supporting the breakdown of otherwise problematic dietary components. However, evidence is moderate rather than strong, and most benefits are noted in populations with specific digestive challenges rather than the general population. There is no significant historical or traditional use of isolated peptidase for gut health, as enzyme supplementation is a relatively modern intervention. In summary, scientific evidence does support the use of peptidase to aid small intestinal digestion, particularly in targeted populations, but more robust, large-scale studies are needed to confirm benefits for broader use.
Other ingredients that support Small Intestines
2'-FucosyllactoseAcemannan
Agrimonia pilosa
Alchemilla
Alchornea
Algal protein
Aloe vera
alpha-galactosidase
Alpha-glycans
amino acids
aminopeptidase
amylase
animal protein
arabinoxylan
ashitaba
asparagus
Asteraceae
Bacillus
bacillus clausii
bacillus coagulans
Bacillus indicus
Bacillus licheniformis
bacillus subtilis
bacteria
bael
bayberry
bee products
berberine
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bile
bile acid
bile salt
bitter principals
black seed
Boerhavia diffusa
bottle gourd
bran
Brassica
broccoli
Brussel sprouts
Buckwheat
butternut
butyrate triglyceride
butyric acid
cape aloe
caprylic acid
carrot
carvacrol
cayenne pepper
Centella triterpenes
chia seed
chickpea protein
chicory
Chitin-Glucan Complex
Cinnamomum
cinnamon
Citrus
Clostridium butyricum
colostrum
corktree
cowpea
cruciferous
curry leaf
Debaryomyces hansenii
diamine oxidase
dioscorea
egg
Egg protein
electrolytes blend (proprietary)
endo-peptidase
Enterococcus
enzyme blend
enzymes blend (proprietary)
Eucheuma
exo-peptidase
fatty acids
fennel
fenugreek
fiber
fiber blend (proprietary)
fig
fish
flavones
flavonoids
flavonols
flaxseed
folate
Foxtail millet
fringetree
fructooligosaccharides (FOS)
fruit
fungal enzymes blend (proprietary)
fungal protease
galactooligosaccharides
galactosidase
ginger
Glucooligosaccharides
glucose
Glutamine
Glutenase
Glycomacropeptides
Glycyrrhizin
goldthread
green banana
green tea
Gymnema
Gymnema sylvestre
herbal blend (proprietary)
honey
immunoglobin G
Immunoglobulin G
intrinsic factor
inulin
isomalto-oligosaccharide
kale
Kefir
kiwi
Kluyveromyces lactis
Kluyveromyces marxianus
Konjac
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-alanyl-L-glutamine
L-glutamine
L. lactis
lactalbumin
lactase
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus helveticus
Lactobacillus johnsonii
Lactobacillus kefiranofaciens
Lactobacillus kefiri
Lactobacillus paracasei
Lactobacillus pentosus
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus sakei
Lactobacillus salivarius
Lactococcus casei
Lactococcus lactis
Lactococcus rhamnosus
Lactoferrin
Legume protein
lemon
Lentil
lingzhi
lipase
lipids
magnesium
maltase
mannans
Marshmallow
Matapalo Tree
medium chain triglycerides (MCT)
Microbial enzymes (proprietary)
Milk Protein
Millet
millet seed
Mimosa
Mineral ascorbate
Monounsaturated fat
Mucilage
Mung bean
Mushroom
N-acetyl-glucosamine
Nigella seed
okra
Oligosaccharides
ox bile
Paenibacillus polymyxa
pancreatin
papaya
parsley
pear
Pediococcus acidilactici
Pediococcus pentosaceus
Peptidase
peptidase (DPPIV)
Peptides
phaseolamin
phellodendron amurense
phenolic compounds
phospholipids
Phyllanthus
phytase
Piperine
polyphenols
polysaccharides
Portulaca
prebiotic blend (proprietary)
probiotics
prolyl endopeptidase (PEP)
Propionibacterium freudenreichii
protease
protein
proteolytic enzymes
Pterocarpus marsupium
pu-er tea
pumpkin
purslane
rice
rockweed
Saccharomyces boulardii
Salacia
Salmon Oil
Sargassum
Scimitar bean
seaweed
Slippery Elm
slippery elm bark
Soy Protein
soybean
Spelt
spinach
streptococcus thermophilus
sucrase
sulforaphane glucosinolate
Tagatose
Taka amylase
Terpenoids
Tiger Nut
trace minerals
tributyrin
turmeric
vitamin A
vitamin B
vitamin D
vitamin D3
Watermelon
xylooligosaccharides
Yacon
Yarrow
Zinc
Other body systems supported by Peptidase
Digestive SystemGastrointestinal Tract
Intestinal System
Small Intestines
