Evidence supporting the use of: Saccharomyces
For the body system: Small Intestines

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Saccharomyces, particularly Saccharomyces boulardii, has significant scientific validation for supporting the small intestine and overall gastrointestinal health. Multiple randomized controlled trials and meta-analyses have shown that S. boulardii can reduce the duration and severity of acute infectious diarrhea, including that caused by Clostridioides difficile and antibiotics. Its mechanism of action involves modulation of gut microbiota, inhibition of pathogenic bacteria, enhancement of intestinal barrier function, and modulation of immune responses in the gut. Specifically for the small intestine, S. boulardii helps maintain the integrity of the mucosal lining, decreases inflammation, and may aid in the prevention and treatment of small intestinal bacterial overgrowth (SIBO) and traveler’s diarrhea. The World Gastroenterology Organisation includes S. boulardii among the probiotics with evidence for effectiveness in certain gastrointestinal disorders. While the majority of evidence is for the management of diarrhea and not for general “support” of the small intestine, the research does indicate a beneficial, protective effect on small intestinal health under stress or infection. Thus, the use of Saccharomyces for supporting the small intestine is scientifically grounded, though it is most justified in the context of specific digestive disturbances rather than healthy individuals.

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Products containing Saccharomyces

We currently have no products on Vitabase that contain this ingredient.