Evidence supporting the use of: Vitamin B1 (thiamin disulfide)
For the body system: Small Intestines

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B1, also known as thiamine (not "thiamin disulfide"—the physiologically active form is thiamine or thiamine pyrophosphate), plays a well-established role in human metabolism, particularly in the breakdown of carbohydrates and the functioning of the nervous system. Its relationship to the small intestine is primarily indirect, stemming from its importance in energy production and maintenance of healthy nerve and muscle function throughout the gastrointestinal tract. Deficiency of thiamine can lead to conditions such as beriberi and Wernicke-Korsakoff syndrome, which can present with gastrointestinal symptoms like anorexia, abdominal discomfort, and impaired motility.

There is some scientific evidence that thiamine is important for gastrointestinal health. Thiamine is absorbed in the small intestine, and its deficiency can negatively affect the motility and function of the gut. Some studies suggest that thiamine supplementation may alleviate certain gastrointestinal symptoms, particularly in people with underlying deficiencies or chronic conditions that impair absorption, such as inflammatory bowel disease or chronic alcoholism. However, there is limited direct evidence or high-quality clinical trials specifically showing that thiamine supplementation benefits the small intestine in otherwise healthy individuals. Most of its use is based on its established role in systemic metabolism and the prevention of deficiency states.

In summary, while thiamine is essential for the normal functioning of the small intestine and overall digestive health, direct supplementation is usually only necessary in cases of deficiency or malabsorption. The scientific evidence supports its importance, but not necessarily its use as a targeted supplement for small intestine health in the absence of deficiency.

More about Vitamin B1 (thiamin disulfide)
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Products containing Vitamin B1 (thiamin disulfide)

We currently have no products on Vitabase that contain this ingredient.