Evidence supporting the use of: Vitamin B9
For the body system: Small Intestines
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Vitamin B9, also known as folate or folic acid (in synthetic form), has scientifically validated roles in supporting the health of the small intestine, although its primary functions are often discussed in the context of cell division, DNA synthesis, and prevention of neural tube defects. Folate is crucial for rapidly dividing cells, which includes the epithelial cells lining the small intestine. These cells turn over quickly and require adequate folate to proliferate and maintain the integrity of the intestinal mucosa. Deficiency in folate can lead to villous atrophy and impaired absorption, which are reversible upon repletion of folate. Clinical research and case studies have shown that folate deficiency may contribute to malabsorption syndromes seen in certain gastrointestinal diseases, such as celiac disease, tropical sprue, and inflammatory bowel disease, all of which can be improved with folate supplementation when deficiency is present.
Furthermore, the small intestine is the primary site for the absorption of folate from the diet. Malabsorption disorders affecting the small intestine can therefore lead to folate deficiency, creating a cycle where poor intestinal health exacerbates folate deficiency, and vice versa. The scientific literature, including reviews and clinical guidelines, supports the use of folate in maintaining and restoring small intestinal mucosal health, especially in cases where deficiency is identified. Therefore, there is strong scientific justification for the use of Vitamin B9 in supporting the small intestine, reflected in a rating of 4 out of 5.
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amylopectin
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bacillus clausii
bacillus coagulans
bacillus subtilis
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berberine
bifidobacterium bifidum
bifidobacterium breve
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colostrum
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l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
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lactase
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