Evidence supporting the use of: Vitamin B9 (Mixed)
For the body system: Small Intestines
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Vitamin B9, also known as folate or folic acid (when synthetic), is essential for numerous metabolic processes, including DNA synthesis and repair, cell division, and amino acid metabolism. Its relationship to small intestine health is indirect but scientifically supported. Folate is absorbed primarily in the proximal small intestine (jejunum). Deficiency can result from malabsorption syndromes (such as celiac disease or Crohn's disease), which damage the intestinal lining and impair absorption. Conversely, adequate folate status supports the rapid turnover of enterocytes (intestinal lining cells), which is necessary for maintaining healthy intestinal mucosa.
While folate is not a direct treatment for small intestine conditions, supplementation is often indicated in diseases causing malabsorption to prevent or correct deficiency. There is scientific evidence that folate is critical for the health of tissues with high cell turnover, such as the intestinal epithelium, and deficiency can contribute to gastrointestinal symptoms like diarrhea and mucosal atrophy. However, folate supplementation is not used to directly treat small intestine diseases but rather to support overall mucosal health and to compensate for losses due to malabsorption. The evidence supporting its use for direct support of small intestine structure or function is therefore moderate, justifying a rating of 2.
References:
- Allen LH. Causes of vitamin B12 and folate deficiency. Food Nutr Bull. 2008.
- NIH Office of Dietary Supplements: Folate Fact Sheet.
Other ingredients that support Small Intestines
2'-Fucosyllactosealoe vera
alpha-galactosidase
amino acids
amylase
amylopectin
asparagus
bacillus clausii
bacillus coagulans
bacillus subtilis
bayberry
berberine
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
broccoli
rice
brussel sprouts
butyrate triglyceride
caprylic acid
carrot
chia seed
chicory
cinnamon
coating
colostrum
turmeric
endo-peptidase
exo-peptidase
fennel
fenugreek
fiber blend (proprietary)
flavonols
flaxseed
folate
fructooligosaccharides (FOS)
fungal protease
ginger
green banana
green tea
gurmar
cellulose
immunoglobin G
inulin
isomalto-oligosaccharide
kale
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-alanyl-l-glutamine
l-glutamine
lactase
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lactoferrin
lemon
lipase
magnesium
marshmallow
medium chain triglycerides (MCT)
microbial enzymes (proprietary)
n-acetyl-glucosamine
okra
ox bile
pancreatin
parsley
pear
peptidase (DPPIV)
phellodendron amurense
phenolic acids
phospholipids
phytase
potato starch
prebiotic blend (proprietary)
prolyl endopeptidase (PEP)
protease
protein
butyric acid
pumpkin
saccharomyces boulardii
sardines
slippery elm bark
soybean
spinach
starch
streptococcus thermophilus
sucrase
sulforaphane glucosinolate
tributyrin
vitamin A
vitamin B
vitamin D
vitamin D3
seaweed
water
watermelon
xylooligosaccharides
zinc
papaya
pterocarpus marsupium
lingzhi
yarrow
bile salt
sodium salt
dioscorea
electrolytes blend (proprietary)
polyphenols
trace minerals
purslane
fungal enzymes blend (proprietary)
millet seed
herbal blend (proprietary)
chickpea protein
enzymes blend (proprietary)
cayenne pepper
ashitaba
Aminopeptidase
Alchornea
Alpha-glycans
Alchemilla
Agrimonia pilosa
Asteracea
Acemannan
Algal protein
Arabinoxylan
Animal protein
Black Seed
Bifidobacterium
Bacillus indicus
Bifidobacterium adolescentis
Brassica
Bran
Bael
Butternut
Bacillus licheniformis
Bile
Bifidobacterium animalis
Bee products
Bitter principals
Bacteria
Bifidobacteria
bile acid
Bacillus
Buckwheat
Boerhavia diffusa
Bottle gourd
Centella triterpenes
Curry leaf
Cowpea
Cinnamomum
Carvacrol
Cape Aloe
Citrus
Cruciferous
Chitin-Glucan Complex
Corktree
Clostridium butyricum
Debaryomyces hansenii
Diamine Oxidase
Enterococcus
Egg
Eucheuma
Enzyme Blend
Egg protein
Fig
Fiber
Flavonoids
Goldthread
Galactosidase
glucose
Milk Protein
Mimosa
Soy Protein
Other body systems supported by Vitamin B9 (Mixed)
BloodBrain
Digestive System
Female Reproductive System
Gastrointestinal Tract
Heart
Immune System
Intestinal System
Nerves
Reproductive System
Skin
Small Intestines