Homalomena species, particularly Homalomena aromatica, have been traditionally used in various Asian medicinal systems for treating sore throat and related upper respiratory ailments. Ethnobotanical surveys and traditional medicine records from regions such as Southeast Asia (notably in Malaysia and Indonesia) indicate that the rhizomes and leaves of Homalomena are prepared as decoctions or pastes, and these preparations are administered orally or used as gargles to relieve throat discomfort, cough, and hoarseness.

The rationale behind its traditional use is largely anecdotal and based on long-standing cultural practices. Some studies have identified the presence of essential oils, flavonoids, and other phytochemicals in Homalomena species, which are believed to possess anti-inflammatory and antimicrobial properties. However, there is a lack of direct clinical evidence or robust pharmacological studies specifically evaluating the efficacy of Homalomena for sore throat in human populations. Most available information comes from traditional knowledge and preliminary phytochemical screenings, rather than from controlled scientific investigations.

In summary, the use of Homalomena for sore throat is primarily justified by traditional use rather than scientific validation. The evidence rating is moderate (2/5), reflecting the presence of historical usage but the absence of rigorous scientific evaluation.