Evidence supporting the use of: Indian nightshade
For the health condition: Sore Throat

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Indian Nightshade (Solanum xanthocarpum), also known as Kantakari, is primarily justified for use in sore throat by traditional medicine systems rather than robust scientific validation. In Ayurvedic texts, Indian Nightshade is described as having anti-inflammatory, expectorant, and antimicrobial properties, and is commonly included in formulations for respiratory ailments, including sore throat, cough, and asthma. Traditional preparations may involve decoctions or powders of the root or fruit, administered orally or used as gargles.

While preclinical studies indicate that extracts of Indian Nightshade possess some antimicrobial activity and may modulate inflammation, clinical trials specifically evaluating its efficacy for sore throat are lacking. The evidence base consists mainly of in vitro and animal studies, which show potential antibacterial effects against pathogens that can cause throat infections, and some reduction in experimentally induced inflammation. However, no large-scale, placebo-controlled human trials have confirmed its benefit for sore throat in humans.

In summary, the use of Indian Nightshade for sore throat is rooted in traditional practices, with limited but suggestive preclinical scientific support. More rigorous clinical studies are needed to confirm its effectiveness and safety for this indication.

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