Meadow sage (Salvia pratensis) has a long history of traditional use for treating sore throat and other minor throat irritations. Recent scientific studies have provided some validation for this use, primarily through investigations of related sage species such as Salvia officinalis (common sage), which shares many phytochemical properties with meadow sage. Sage extracts, including those from meadow sage, contain active compounds such as rosmarinic acid, flavonoids, and essential oils known for their anti-inflammatory, antimicrobial, and astringent properties.

Clinical research, particularly involving sage-based throat sprays or gargles, has demonstrated that these preparations can reduce throat pain and inflammation in cases of pharyngitis and sore throat. For example, a randomized controlled trial using a Salvia officinalis spray found significant symptom relief compared to placebo. While direct clinical trials with Salvia pratensis are limited, the phytochemical similarities and traditional use suggest comparable effects.

In summary, the use of meadow sage for sore throat is supported by both traditional usage and a moderate level of scientific evidence, bolstered mainly by studies of closely related sage species. The evidence rating is moderate due to the reliance on indirect studies; further research specifically on meadow sage would strengthen the scientific basis for its use.