Evidence supporting the use of: Umckaloabo
For the health condition: Sore Throat
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Umckaloabo (Pelargonium sidoides) for Sore Throat: Evidence Overview
Umckaloabo, an extract from the roots of Pelargonium sidoides, is traditionally used in South African herbal medicine for respiratory tract ailments. In recent years, clinical interest has focused on its application for acute respiratory infections, including sore throat, which often accompanies conditions like acute pharyngitis, tonsillitis, and the common cold.
Several randomized, placebo-controlled clinical trials and meta-analyses have evaluated the efficacy of Umckaloabo for acute respiratory tract infections. A notable Cochrane review (2013, updated 2018) concluded that Pelargonium sidoides extract may reduce the severity and duration of symptoms in acute sore throat, particularly when these symptoms are part of a broader upper respiratory tract infection. The mechanism is thought to involve immunomodulatory and antimicrobial effects, although the exact pathways remain under investigation.
While the overall methodological quality of studies varies and some have limitations (such as short duration and industry sponsorship), the evidence base is stronger than for many other herbal remedies. The extract is approved in several European countries for the treatment of acute bronchitis and, by extension, is often used for sore throat and related symptoms.
In summary, there is moderate scientific evidence supporting the use of Umckaloabo for sore throat, mainly when it occurs as part of a broader respiratory tract infection. The effect size is modest, and further high-quality studies would be valuable.
Other ingredients used for Sore Throat
AcaciaAdenophora
Agastache
Agrimony
Alchemilla
Alchornea
Allspice
Allyl isothiocyanate
Aloe vera
alpha-pinene
alpha-terpineol
Alstonia scholaris
Amomum
Andrographis
anise
Arisaema
asafoetida
Asarum heterotropoides
Asarum sieboldii
atractylodes
balloon flower
Baphicacanthus cusia
bee propolis
Belamcanda
betel
black pepper
boneset
Bougainvillea
Bryonia
Buddha\'s hand
calamus
camphor oil
cardamom
Carlina
carvone
chaff flower
chamomile
Cistus
coltsfoot
cubeb
culvers Root
dodeca-2E, 4E, 8Z, 10Z/tetraenoic acid isobutylamide
dog rose
echinacea purpurea
Elder
elderberry
elecampane
English horsemint
fernbush
ficin
fleabane
flowering quince
fritillaria
fritillary
genipap
Glehnia littoralis
glehnia root
goldthread
Guaco
Heartsease
Hedychium spicatum
Homalomena
honey loquat syrup
honeydew
honeysuckle
horehound
Houttuynia
hyssop
Indian nightshade
inula racemosa
Japanese sophora
Javanese Long Pepper
Kachnar
Labdanum
licorice root
Lilium polyphyllum
liverwort
Lomatium
Lysimachia
manzanita
Marjoram
Marsh Tea
Marshmallow
Matico
Meadow sage
Meadowsweet
Mentha haplocalyx
Milkweed
Mint
Mountain mahogany
Mullein
Orsa salt
Pepper Bark Tree
Phragmites
Pimpinella
pistacia integerrima gall
platycodon root
Premna
Rhus coriaria
sage
Sambucus nigra
Sandy Everlasting
Sassafras
Savory
Sichuan pepper
slippery elm bark
Speedwell
Spikenard
Spilanthes
spruce
Stone Root
Streptococcus salivarius
sweetgums
Tannins
Tonka Bean
Trailing Arbutus
Umckaloabo
vitamin C
Wood betony
Yarrow
Yellow root
Yerba santa
zhejiang fritillary
Zinc
Other health conditions supported by Umckaloabo
AdenitisBronchitis
Colds (general)
Colds (prevention)
Colds (with fever)
Infection
Infection (bacterial)
Influenza
Sore Throat
Tonsillitis
Wounds and Sores
