Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Adrenaline (also known as epinephrine) is a well-characterized endogenous catecholamine that acts as both a hormone and neurotransmitter within the body. Its role in the Specific Neurotransmitters body system, particularly in the central and peripheral nervous systems, is scientifically validated. Adrenaline is synthesized and released from the adrenal medulla and certain neurons. It binds to adrenergic receptors (alpha and beta subtypes) on various target tissues, including neurons, influencing neurotransmitter release and neuronal excitability.

In medical practice, exogenous adrenaline is administered in acute settings such as anaphylaxis, cardiac arrest, and severe asthma attacks, due to its rapid action on adrenergic receptors. While its primary clinical uses are not to broadly support neurotransmitter function, its mechanisms of action are central to neurotransmitter systems, especially those involving adrenergic signaling.

The evidence for adrenaline’s role in supporting the neurotransmitter body system is robust, with numerous studies detailing its effects on synaptic transmission, neuronal signaling, and modulation of other neurotransmitters like dopamine and norepinephrine. Its use is based on an extensive understanding of neurophysiology and pharmacology, rather than tradition or anecdote.

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