Bacopa monnieri, also known as Brahmi, is a traditional Ayurvedic herb that has gained scientific interest for its effects on the nervous system, particularly regarding neurotransmitter activity. A number of clinical and preclinical studies have examined Bacopa's influence on cognitive function, memory, and neurochemical modulation. Scientific evidence suggests that Bacopa monnieri can modulate neurotransmitters such as serotonin, dopamine, and acetylcholine, all of which are key to cognitive processes and mood regulation. For example, animal studies have shown that Bacopa extract can increase the levels of these neurotransmitters in the brain, partially explaining its nootropic and adaptogenic effects. Human trials, though fewer in number, have demonstrated improvements in memory, attention, and cognitive processing, which may be associated with these neurochemical modulations.

A systematic review published in Current Neuropharmacology (2016) concluded that Bacopa has the potential to enhance cognitive performance, possibly through antioxidant effects and modulation of cholinergic and monoaminergic systems. While more high-quality, large-scale human trials are needed to confirm these findings, the current body of evidence supports the use of Bacopa monnieri to support the "Specific Neurotransmitters" body system, with a moderate to strong scientific basis.