Evidence supporting the use of: Beta phenethylalamine
For the body system: Specific Neurotransmitters

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Beta-Phenethylamine (PEA) is a naturally occurring compound found in the human brain and in certain foods such as chocolate. It acts as a neuromodulator and is structurally similar to amphetamines. PEA is known to promote the release of neurotransmitters such as dopamine and norepinephrine, which are involved in mood, attention, and alertness. Some studies suggest that PEA levels may be lower in individuals with certain neuropsychiatric conditions, such as depression and attention deficit hyperactivity disorder (ADHD). Supplementation with PEA has been explored as a way to enhance mood and cognitive function; however, the evidence from clinical trials remains limited and preliminary.

Oral PEA is rapidly metabolized by the enzyme monoamine oxidase-B (MAO-B), resulting in low bioavailability and a short duration of action. Some research has explored the use of MAO-B inhibitors to prolong its effects. The most robust evidence comes from small-scale studies and anecdotal reports, rather than large, well-controlled clinical trials. Thus, while there is a plausible scientific rationale for using PEA to support the "Specific Neurotransmitters" body system, the actual clinical evidence supporting its efficacy is limited, and more research is needed to determine its safety and effectiveness in this context.

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Other body systems supported by beta phenethylalamine

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Specific Neurotransmitters

Products containing beta phenethylalamine

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