Evidence supporting the use of: Chocolate
For the body system: Specific Neurotransmitters

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Chocolate, particularly dark chocolate, contains several bioactive compounds that can influence neurotransmitters, thus supporting the "Specific Neurotransmitters" body system. The primary compounds of interest are flavonoids, caffeine, theobromine, and small amounts of phenylethylamine and tryptophan. Scientific studies indicate that flavonoids in cocoa can cross the blood-brain barrier and have neuroprotective and neuromodulatory effects. These flavonoids may enhance cerebral blood flow, stimulate neurogenesis, and upregulate brain-derived neurotrophic factor (BDNF), indirectly supporting the synthesis and function of neurotransmitters like dopamine and serotonin.

Additionally, cocoa contains methylxanthines such as caffeine and theobromine, which can modulate levels of neurotransmitters including adenosine, noradrenaline, and dopamine, leading to mild stimulant and mood-enhancing effects. Some research suggests that chocolate consumption can acutely elevate serotonin and endorphin levels, contributing to improved mood and perceived well-being. However, while several studies point to these effects, the magnitude and clinical significance are moderate, and effects are often transient or modest.

Overall, the body of evidence supports a connection between chocolate and neurotransmitter modulation, but more research is needed to establish definitive therapeutic effects. Thus, the evidence rating is 3 out of 5, reflecting moderate scientific support.

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