Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Fish, including shellfish, are justified for supporting the specific neurotransmitters body system based on scientific evidence. Fish, particularly fatty fish such as salmon, sardines, and mackerel, are rich sources of omega-3 polyunsaturated fatty acids, especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These nutrients are critical for brain health and have been shown to directly influence neurotransmitter function. DHA is a key structural component of neuronal cell membranes and is involved in synaptic plasticity and signal transduction, which are essential for neurotransmission. Multiple clinical studies and meta-analyses have found that increased fish or omega-3 intake is associated with improved mood, cognitive function, and a lower risk of neuropsychiatric disorders such as depression and anxiety, which are mediated by neurotransmitter systems (notably serotonin and dopamine). Shellfish also provide vitamin B12, zinc, and selenium, all of which are involved in neurotransmitter synthesis and regulation. While fish consumption is traditionally associated with brain health in some cultures, the modern scientific evidence for its role in supporting neurotransmitter systems is robust and well-documented in peer-reviewed research. However, it should be noted that while the evidence is strong for general support of neurotransmitter health, specific effects on individual neurotransmitters may vary, and more research is needed to clarify these mechanisms.

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