Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Collagen peptides are sometimes used to support the health of spinal disks, primarily due to their general role in connective tissue health. Collagen is a major structural protein in the body, present in cartilage, ligaments, and intervertebral disks (which are composed of a nucleus pulposus and annulus fibrosus, both containing collagen fibers). Some small clinical studies and preclinical research suggest that oral collagen peptide supplementation may improve markers of joint and connective tissue health, such as skin elasticity and joint pain in osteoarthritis. However, direct, high-quality scientific evidence specifically linking collagen peptide supplementation to improved spinal disk structure, function, or regeneration is limited.

Animal studies indicate that collagen peptides may stimulate extracellular matrix production in cartilage and intervertebral disk tissue. Human studies on disk health are scarce; most clinical trials focus on joints or skin. A 2022 review (Khatri et al.) noted a lack of robust clinical evidence for efficacy in spinal disk disorders, though they noted the theoretical plausibility due to collagen's role in disk structure. Overall, while there is some scientific rationale and preliminary evidence, the direct support for the use of collagen peptides specifically for spinal disk health remains weak and requires more robust, targeted research.

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