The use of Pacific Dogwood (Cornus nuttallii) for treating sprains is primarily rooted in traditional medicine rather than supported by scientific evidence. Indigenous peoples of the Pacific Northwest have historically used various parts of the Pacific Dogwood tree, including bark and leaves, in poultices and topical applications to address external injuries such as bruises and sprains. These traditional practices are often based on empirical observations and cultural transmission rather than formal clinical studies.

However, there is a lack of rigorous scientific research or clinical trials to validate the efficacy of Pacific Dogwood in the treatment of sprains. Modern pharmacological literature does not list Pacific Dogwood as an established remedy for musculoskeletal injuries, and there are no known active compounds in this species that have been conclusively shown to aid in the healing of sprains.

In summary, while the use of Pacific Dogwood for sprains is documented in traditional medicine among certain Indigenous groups, this practice is not backed by scientific validation. As such, its current use for sprains should be viewed as a traditional remedy with limited supporting evidence.