Evidence supporting the use of: Solomon's seal
For the health condition: Sprains
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Solomon’s seal (Polygonatum spp.) has a long history of traditional use, especially in Western herbalism and Traditional Chinese Medicine (TCM), for addressing musculoskeletal issues such as sprains, bruises, and joint discomfort. Herbalists have historically applied poultices, salves, or infusions of Solomon’s seal rhizome to sprained joints or ligaments with the belief that it helps “knit” tissues, reduce swelling, and promote healing. This traditional reputation is reflected in 19th and early 20th-century herbal literature, with practitioners like Nicholas Culpeper and more recent herbalists recommending it for injuries involving connective tissues.
However, scientific evidence supporting Solomon’s seal specifically for treating or speeding the recovery of sprains is minimal. Some laboratory studies show the plant contains saponins, flavonoids, and allantoin, compounds known for anti-inflammatory or tissue-repairing properties. Yet, there are no robust clinical trials or biomedical studies directly evaluating its effectiveness for sprain recovery in humans. Most modern sources reference anecdotal reports and traditional usage rather than empirical data. Therefore, while its use is well-rooted in herbal tradition and some plausible mechanisms exist, scientific validation for this specific indication is lacking, justifying a modest evidence rating.
Other ingredients used for Sprains
Allspicebromelain
chymotrypsin
Cissus quadrangularis
collagen
turmeric
endo-peptidase
horsetail
Methylsulfonylmethane (MSM)
serratiopeptidase
Trypsin
vitamin C
white willow
solomon's seal
Wintergreen
camphor oil
Abies spectabilis
arnica
clematis
Achyranthes
Anemone
Aescin
Actaea spicata
aspen
Alstonia macrophylla
Brassaiopsis glomerulata
bai ji
big quaking grass
bogbean
black poplar
barbary matrimony vine
cypress
Collinsonia
Drynaria
Dimethyl sulfoxide (DMSO)
Dipsacus
enzyme blend
fibrinase
giant trillium
Glycosaminoglycans
hairy arnica
Harpagoside
joe-pye
Malay bush
Mucopolysaccharide
Sinapis arvensis
Salicin
Sida cordifolia
Spatholobus
Sweet Clover
Stone Root
Willow
Zingibain
Other health conditions supported by solomon's seal
Abdominal PainArthritis
Backache
Bruises (healing)
Burns and Scalds
Cuts
Digestion (poor)
Edema
Inflammation
Injuries
Ligaments (torn or injured)
Pain (general remedies for)
Sprains
Wounds and Sores