Evidence supporting the use of: Andrographis
For the health condition: Staph Infections

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Andrographis paniculata, commonly known as "king of bitters," has a long history of use in traditional Ayurvedic and Chinese medicine, primarily for its purported anti-inflammatory, antipyretic, and antimicrobial properties. In traditional systems, Andrographis is sometimes used to treat infections, including those that may be caused by Staphylococcus species, though references are typically broad and not specific to "staph" as understood in modern microbiology. Its inclusion in traditional formulas for skin and wound infections may be related to its general antimicrobial reputation.

Modern scientific studies have investigated the antibacterial effects of Andrographis extracts and its main active compound, andrographolide. Some in vitro (laboratory) research has shown that these extracts can inhibit the growth of Staphylococcus aureus, including some antibiotic-resistant strains. However, these findings are preliminary and largely limited to cell culture studies; there is a lack of robust clinical trials or in vivo evidence demonstrating that Andrographis is effective for treating staph infections in humans. As such, while traditional use supports Andrographis for a variety of infections, scientific validation specifically for Staphylococcus infections remains weak.

In summary, Andrographis is traditionally used for infections and has limited laboratory evidence supporting antibacterial activity against Staphylococcus species, but clinical evidence is lacking.

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