Evidence supporting the use of: Hydrogen peroxide
For the health condition: Staph Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Hydrogen peroxide has a long history as an antiseptic agent, used to disinfect wounds and prevent or treat superficial skin infections. Its mechanism of action involves releasing oxygen free radicals that can damage bacterial cell components, leading to microbial death. Several in vitro studies have demonstrated that hydrogen peroxide is effective in killing Staphylococcus aureus, the bacterium responsible for most staph infections. However, the clinical evidence supporting its use for established staph infections in humans is limited.

Topical hydrogen peroxide is sometimes used for minor cuts, abrasions, or superficial skin infections, but its efficacy compared to other antiseptics or antibiotics is not well supported by controlled trials. Some studies suggest that hydrogen peroxide may delay wound healing due to cytotoxic effects on human cells, especially at higher concentrations. Medical guidelines typically do not recommend hydrogen peroxide as a primary treatment for staph infections, particularly for deeper or more serious infections, where systemic antibiotics are preferred.

In summary, while there is a scientific basis for hydrogen peroxide’s antibacterial activity, its use in treating staph infections is supported only for minor superficial wounds and is considered less effective or more damaging than other antiseptics or modern antibiotics. The overall clinical evidence is limited, reflected in a moderate-low evidence rating.

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Products containing Hydrogen peroxide

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