Evidence supporting the use of: Lupulone
For the health condition: Staph Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lupulone is a beta acid derived from hops (Humulus lupulus) and is known for its antimicrobial properties. Several in vitro studies have shown that lupulone and related hop acids possess significant antibacterial activity against Gram-positive bacteria, including Staphylococcus aureus, which is a common cause of staph infections. In particular, research has demonstrated that lupulone can disrupt bacterial cell membranes and inhibit bacterial growth, with some studies suggesting potential efficacy even against methicillin-resistant S. aureus (MRSA) strains.

However, despite promising laboratory results, there is currently limited direct clinical evidence to support the use of lupulone as a treatment for staph infections in humans. The bulk of the evidence is preclinical, consisting of laboratory (in vitro) studies and a few animal studies. There are no robust human clinical trials demonstrating safety or efficacy in treating or supporting staph infections with lupulone. As such, while the scientific rationale exists and the mechanism of action against S. aureus is plausible, the evidence remains at an early stage. Lupulone has not been adopted as a standard or recommended therapy for staph infections in clinical practice.

In summary, the use of lupulone for staph infections is justified by preclinical scientific evidence, but its efficacy and safety for this purpose in humans remain unproven.

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Products containing lupulone

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