Evidence supporting the use of: Ovotransferrin
For the health condition: Staph Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ovotransferrin, a glycoprotein found in egg whites, is known for its strong iron-binding properties and antimicrobial activity. Scientific interest in ovotransferrin as an antimicrobial agent comes from its ability to sequester iron, making it unavailable to bacteria, including Staphylococcus aureus (the most clinically significant Staph species), which require iron for growth and virulence. Several in vitro studies have demonstrated that ovotransferrin can inhibit the growth of S. aureus and other pathogens by creating iron-limited conditions.

Additionally, ovotransferrin exhibits direct bacteriostatic and bactericidal effects, potentially by destabilizing bacterial cell membranes or generating reactive oxygen species. However, most of the research to date has been conducted in laboratory settings (test tubes or cell cultures), not in humans or animal models of infection. There are no clinical trials or robust in vivo studies demonstrating that dietary or supplemental ovotransferrin is an effective treatment or adjunct therapy for Staph infections in humans.

In summary, while ovotransferrin does have scientifically validated antimicrobial properties against S. aureus in vitro, the current evidence base is preliminary, lacking clinical validation. Its use as a treatment for Staph infections is based on mechanistic and laboratory data, not on clinical trials or established medical practice. Thus, the evidence rating is moderate (2/5), reflecting promising but unproven potential.

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Products containing Ovotransferrin

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