Evidence supporting the use of: Simaruba
For the health condition: Staph Infections
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Simaruba (commonly referring to Simarouba amara or Simarouba glauca) is a medicinal plant traditionally used in Central and South American herbal medicine, primarily for its purported antimicrobial, antiparasitic, and anti-inflammatory properties. Its bark and leaves have been used in folk medicine to treat a range of infections, including dysentery, malaria, and other gastrointestinal illnesses. However, there is little direct historical documentation specifically supporting its use against Staphylococcus (Staph) infections. The linkage to Staph infections is more an extension of its broad traditional use for "infections" rather than targeted evidence.
From a scientific perspective, there are minimal studies evaluating Simaruba extracts specifically against Staphylococcus aureus or related Staph species. A few in vitro studies on related Simaroubaceae plants suggest some antibacterial activity, but these are limited, preliminary, and not focused on clinical isolates of Staph. There is no robust clinical or laboratory evidence to confirm its efficacy or safety for treating Staph infections in humans. Therefore, its use for this purpose is primarily justified by tradition rather than scientific validation, and the traditional evidence is weak and not specific to Staph infections.
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