Evidence supporting the use of: Streptomyces fradiae
For the health condition: Staph Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Streptomyces fradiae is a bacterium renowned for its ability to produce antibiotics, notably neomycin. Neomycin is an aminoglycoside antibiotic with documented efficacy against a range of Gram-positive and Gram-negative bacteria, including some strains of Staphylococcus aureus (the causative agent of many staph infections). The discovery of neomycin in the late 1940s led to its widespread use in topical treatments for skin infections and in some oral and ophthalmic preparations. Its mechanism of action involves binding to the bacterial 30S ribosomal subunit, thereby inhibiting protein synthesis and leading to bacterial cell death. While neomycin is effective in vitro against many staphylococcal strains, resistance can occur, and its systemic use is limited due to toxicity concerns (notably nephrotoxicity and ototoxicity). Nonetheless, the use of Streptomyces fradiae as a source organism for neomycin is well-supported by scientific literature, and neomycin-containing products are established in the treatment and prevention of superficial staph infections. The evidence rating is not maximal (5/5) because of concerns regarding resistance and toxicity, but the foundational scientific validation of its antibacterial activity against staph species is robust.

More about Streptomyces fradiae
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Other health conditions supported by Streptomyces fradiae

Antibiotics (alternatives to)
Infection (bacterial)
Staph Infections

Products containing Streptomyces fradiae

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