Artichoke (Cynara scolymus) leaf extract has a long history of traditional use for digestive complaints, but its use is also supported by modern scientific research. Artichoke extract is primarily used to support the stomach and digestive system by stimulating bile production, which can aid in the digestion of fats and improve overall digestive comfort. Several randomized controlled trials and systematic reviews have demonstrated that artichoke leaf extract can reduce symptoms of functional dyspepsia (indigestion), such as bloating, nausea, and abdominal pain. For example, a double-blind, placebo-controlled trial published in Alimentary Pharmacology & Therapeutics (2003) found significant improvement in dyspeptic symptoms among participants taking artichoke extract compared to placebo. The active compounds, such as cynarin and chlorogenic acid, are believed to be responsible for these effects by promoting choleresis (bile flow) and exerting mild antispasmodic activity.

Systematic reviews, including one from Phytomedicine (2015), conclude that artichoke extract is effective and well-tolerated for the relief of dyspeptic symptoms, though more large-scale studies would further clarify its role. As such, the use of artichoke for supporting the stomach and digestive system is justified by both tradition and scientific evidence, with current research supporting a moderate-to-strong level of efficacy.